Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p56 | (1) | ICCBH2015

Abnormal functional responses of osteoblasts to leptin in adolescent idiopathic scoliosis

Tam Elisa Man Shan , Wang Zhiwei , Lee Wayne , Tang Shengping , Kar-Hing Yeung , Tsz-Ping Lam , Ng Bobby Kin Wah , Cheng Jack Chun Yiu

Objectives: Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional structural deformity of the spine and its etiology remains unknown. Girls with AIS have taller stature, longer arm span, lower BMI, and generalized osteopenia. Leptin has been postulated as one of the etiologic factors of AIS because of its important physiological functions in neuro-osseous development affecting skeletal growth, bone metabolism, energy expenditure and body composition. Previous st...

ba0004p75 | (1) | ICCBH2015

To predict curve progression in newly diagnosed AIS girls -- how good can bone mineral density do?

Yip Benjamin Hon Kei , Yu Fiona Wai Ping , Hung Vivian Wing Yin , Tam Elisa Man Shan , Lam Tsz Ping , Qin Lin , Ng Bobby Kin Wah , Cheng Jack Chun Yiu

Introduction and objective: Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity with lateral curvature of ≧10 degree measured by Cobb angle. Previous studies reported that ~30% of female AIS patients had systemic osteopenia which could persist beyond skeletal maturity and that was one of the important prognostic factors. The aim of this study is to investigate the incremental prognostic value of osteopenia on curve progression in AIS as defined...

ba0006oc8 | (1) | ICCBH2017

Effective therapeutic control of curve progression using calcium and vitamin D supplementation for adolescent idiopathic scoliosis – a randomized double-blinded placebo-controlled trial

Lam Tsz Ping , Yip Benjamin Hon Kei , Man Gene Chi Wai , Lee Wayne YW , Tam Elisa Man Shan , Lee Kwong Man , Yu Fiona Wai Ping , Ng Bobby Kin Wah , Cheng Jack Chun Yiu

Objectives: Adolescent Idiopathic Scoliosis (AIS) is associated with low bone mass. This study aimed at evaluating the therapeutic effect and its determinants of Ca+Vit-D supplementation in improving bone strength and preventing curve progression in AIS.Methods: This was a randomized double-blinded placebo-controlled trial recruiting AIS girls (11–14 years old, Tanner stage<IV) with femoral neck BMDZ-scores<0 and Cobb angle≥15°. 3...

ba0004p76 | (1) | ICCBH2015

Bone quality in severe adolescent idiopathic scoliosis -- quantitative computed tomography of lumbar spine vs high-resolution peripheral quantitative computed tomography of the distal radius: a pilot study

Yu Fiona Wai Ping , Shi Lin , Wang Defeng , Hung Vivian Wing Yin , Choy Wing Yee , Hui Steve Cheuk Ngai , Lee Pak Yin , Tam Elisa Man Shan , Lam Tsz Ping , Qin Lin , Ng Bobby Kin Wah , Chu Winnie Chiu Wing , Griffith James , Cheng Jack Chun Yiu

Introduction and objective: Adolescent idiopathic scoliosis (AIS) is a structural spinal deformity characterized by 3D deformity with lateral curvature of ≧10° as measured by Cobb angle and is predominately seen in girlsaged between 10 and 16-years-old. Low bone mass has been found to be a significant prognostic factor for curve progression in AIS.In our hospital, computed assisted navigation is used for intraoperative pedicle screw placement...